Talks

Cellular, molecular and vascular alterations induced by apnea of prematurity in the murine cerebellum

Neurodevelopment

Cerebellum

Apnea of Prematurity

Intermittent Hypoxia

Oxidative Stress

Transcriptomics

Histology

This work focuses on the effects of apnea of prematurity on the development of the cerebellum in the perinatal period.

Cellular and molecular alterations induced by Apnea of Prematurity in the murine cerebellum

ISTW: Disabilities and Inclusion

Molecular Neurosciences

Neurodevelopment

Cerebellum

Apnea of Prematurity

Apnea of prematurity is responsible for long lasting neurological impairments and current measures are insufficient to treat and understand this disability-causing phenomenon.

Therapeutic potential of neurotrophic factors on cellular and molecular alterations induced by Apnea of Prematurity in the murine cerebellum

NBISE Doctoral Days

Cerebellum

Apnea of Prematurity

Neurotrophic Factors

Cell Differentiation

Synaptic Activity

Laser capture microdissection and RT-qPCR enables us to better understand how different cerebellar cell types are affected by our intermittent hypoxia protocol.

Posters

Apnea of Prematurity induces molecular, cellular, and vascular alterations in the murine cerebellum: focusing on angiogenesis

NBISE Doctoral Days

Transcriptomics

Cerebellum

Hypoxia

RT-qPCR

Intermittent hypoxia in the cerebellum is correlated with changes in the expression of angiogenesis-related genes and in the establishment of the cerebellar vascular network.

Effects of perinatal hypoxia on oxidative stress-related gene expression in the murine cerebellum

LARC’19 conference

Transcriptomics

Cerebellum

Hypoxia

RT-qPCR

Our research shows that the oxidative stress-related damage to the cerebellum is greater with repeated episodes of hypoxia-reoxygenation.