Research Projects

Research projects I am or was involved in

AD-CORE

Alzheimer's Disease: Cellular Origins and Reelin Effects
Molecular Neurosciences
Neurodegeneration
Alzheimer's Disease
Cell Culture
Transcriptomics
This project aims to elucidate the major molecular factors causing early AD pathology by developping a new type of human neuron-specific culture protocol.

Light sheet microscopy of the vascular network in a P8 mouse

Vasc-AoP

Effects of Apnea of Prematurity on vascularization
Cerebellum
Vascularisation
Hypoxia
RT-qPCR
Transparisation
Immunohistochemistry
This project evaluates the impact of apnea of prematurity on cerebellar vascular development, using intermittent hypoxia in a murine model.

Peptide-receptor interaction

PC-Pep

Neuropeptides and receptor expression during Purkinje cell development
Molecular Neurosciences
Neurodevelopment
Cerebellum
Peptides
Bioinformatics
Purkinje Cells
This project studied the expression of several neuropeptides and their receptors on Purkinje cells a mouse model of cerebellar development.

Circular plot illustrating the impact of the multiple genes tested on several key biological pathways

DE-AoP

Developmental effects of Apnea of Prematurity
Molecular Neurosciences
Neurodevelopment
Cerebellum
Hypoxia
Bioinformatics
Transcriptomics
RT-qPCR
This project studies the underlying molecular and cellular mechanisms of apnea of prematurity at play during cerebellar development, using intermittent hypoxia in a mouse model.

Immunohistochemistry marking of a mouse cerebellum

LT-AoP

Long Term effects of Apnea of Prematurity
Molecular Neurosciences
Neurodevelopment
Cerebellum
Hypoxia
Bioinformatics
Immunohistochemistry
This project studied the impact of apnea of prematurity on cerebellar development and the long-term functional deficits resulting from it, using intermittent hypoxia in a mouse model.

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